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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 383035Generated: October 25, 2026

1-Acetoxy-2-bromoethane → 5-[N'-(2-Acetoxyethyl)-2-acetoxypropionylamino]-3-acetoxymethyl-N-(2,3-di-acetoxypropyl)-2,4,6-triiodobenzamide

https://huagongshe.com/reaction/383035

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Acetoxy-2-bromoethaneHCID 13564—
Reactant5-(2-Acetoxypropionylamino)-3-acetoxymethyl-N-(2,3-diacetoxypropyl)-2,4,6-triiodobenzamideHCID 18429188—
Product5-[N'-(2-Acetoxyethyl)-2-acetoxypropionylamino]-3-acetoxymethyl-N-(2,3-di-acetoxypropyl)-2,4,6-triiodobenzamideHCID 1842926395%

Reaction Steps

5-(2-Acetoxypropionylamino)-3-acetoxymethyl-N-(2,3-diacetoxypropyl)-2,4,6-triiodobenzamide was alkylated with 2-bromoethyl acetate according to the general procedure described in Example 25a. After work up the product was isolated in 95% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310243B1
Source datasetuspto-grants-2001_10
ORD IDord-b51268045d70438cb8b8a7b18ee9e5ce
Source noteuspto-grants-2001_10