Lithium Bromide → HCID 18429216, compound

HRID 383059Notes

Reaction equation

HRID 383059 reaction equation
[C:1]([O:4][CH:5]([CH:9]([O:15][C:16](=[O:18])[CH3:17])[CH2:10][O:11][C:12](=[O:14])[CH3:13])[C:6](Cl)=[O:7])(=[O:3])[CH3:2].[Br-:19].[Li+]>C(Cl)Cl>[C:1]([O:4][CH:5]([CH:9]([O:15][C:16](=[O:18])[CH3:17])[CH2:10][O:11][C:12](=[O:14])[CH3:13])[C:6]([Br:19])=[O:7])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 82050Lithium BromideHCID 18429135HCID 18429135, compound

Product 1

HCID 18429216HCID 18429216, compoundYield 97.5%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2,3,4-Triacetoxybutanoyl chloride (39.9 g, 0.142 mol), prepared according to the literature procedure Glattfeld, J. and Kribben, B., J.Am. Chem. Soc. 61 (1939) 1720) was mixed with lithium bromide (30.9 g, 0.356 mol) in methylene chloride (400 ml) and stirred at ambient temperature for 24 h. The mixture was filtered, the solid was washed with additional methylene chloride (50 ml) and the filtrate was evaporated at ambient temperature to give 45 g (97%) of the crude product as an oil.

Workup

  1. filtrationThe mixture was filtered
  2. washthe solid was washed with additional methylene chloride (50 ml)
  3. customthe filtrate was evaporated at ambient temperature

Sources & evidence

ORD record
ord-c5463b38b25a4062bb1e29dca52c1b80
Source dataset
uspto-grants-2001_10
Patent number
US06310243B1

Reaction notes

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