4-Bromotoluene → 4-Methyl-4'-nitro-1,1'-biphenyl

HRID 383069Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.Br[C:12]1[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=1>>[N+:8]([C:5]1[CH:6]=[CH:7][C:2]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=2)=[CH:3][CH:4]=1)([O-:10])=[O:9]

Participants

Reactant 2

HCID 78054-Bromotoluene

HCID 114661-Bromo-4-nitrobenzene

Product 1

HCID 98131714-Methyl-4'-nitro-1,1'-biphenyl

Procedure

The title compound was prepared by Suzuki coupling of 1-bromo-4-nitrobenzene and 1-bromo-4-methylbenzene.

Sources & evidence

ORD record: ord-5d9e7ea65eee4b4ab6cf3255e9c18f1d
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06310095B1

Reaction notes

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