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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 383112Generated: October 31, 2026

(4R)-3-[(tert-butoxy)carbonyl]-1,3-thiazolidine-4-carboxylic acid → [4-(N-tert-butoxycarbonyl-(R)-thiazolidin-4-ylcarbonyl)amino-2-phenylbenzoyl]methionine methyl ester

https://huagongshe.com/reaction/383112

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4R)-3-[(tert-butoxy)carbonyl]-1,3-thiazolidine-4-carboxylic acidHCID 688405—
ReactantN-(4-Amino-2-phenylbenzoyl)methionine methyl esterHCID 18666758—
Product[4-(N-tert-butoxycarbonyl-(R)-thiazolidin-4-ylcarbonyl)amino-2-phenylbenzoyl]methionine methyl esterHCID 54440271—

Reaction Steps

The desired compound was prepared by coupling of N-tert-butoxycarbonyl-(R)-(−) thiazolidine-4-carboxylic acid, prepared as in Example 164A with [4-amino-2-phenylbenzoyl]methionine methyl ester (compound 8) according to the method of Example 163D.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310095B1
Source datasetuspto-grants-2001_10
ORD IDord-6d218c732f0e47ef8533799824ed25d3
Source noteuspto-grants-2001_10