Ethanol → HCID 25002234, compound

HRID 383236Notes

Reaction equation

HRID 383236 reaction equation
O[C:2]1[C:11]([CH3:12])=[C:10]2[C:5]([CH:6]=[C:7]([C:13]3[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[C:15]([O:21][CH3:22])[CH:14]=3)[CH2:8][O:9]2)=[CH:4][CH:3]=1.[CH2:23]([NH2:30])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1.[CH2:31]=[O:32].[CH2:33](O)C>>[CH2:23]([N:30]1[CH2:33][C:3]2[CH:4]=[C:5]3[C:10](=[C:11]([CH3:12])[C:2]=2[O:32][CH2:31]1)[O:9][CH2:8][C:7]([C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[C:15]([O:21][CH3:22])[CH:14]=1)=[CH:6]3)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

5

Reactant 4

HCID 702EthanolHCID 712FormaldehydeHCID 7504BenzylamineHCID 57871385HCID 57871385, compound

Product 1

HCID 25002234HCID 25002234, compoundYield 15%

Procedure

7-Hydroxy-3′,4′-dimethoxy-8-methylisoflav-3-ene (155 mg, 0.52 mmol) was dissolved in ethanol (2.5 ml). Benzylamine (0.07 ml, 023 mmol) was added followed by formaldehyde solution (0.6 ml, 8.06 mmol, 37% wt.). The reaction was stirred at room temperature for 2 days. The precipitate was collected to afford the title compound (33 mg, 15%).

Workup

  1. customThe precipitate was collected

Sources & evidence

ORD record
ord-61bfacac83a94dfc9e71fe3181af57f4
Source dataset
uspto-grants-2013_02
Patent number
US08367659B2

Reaction notes

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