Ethanol → HCID 25007594, compound

HRID 383239Notes

Reaction equation

HRID 383239 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][CH:18]=1)[C:5]1[CH2:6][O:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10](O)[CH:9]=2.[NH2:19][C:20]1[CH:25]=[CH:24][C:23]([CH3:26])=[CH:22][CH:21]=1.[CH2:27]=[O:28].[CH2:29](O)C>>[C:23]1([CH3:26])[CH:24]=[CH:25][C:20]([N:19]2[CH2:29][C:11]3[CH:12]=[C:13]4[C:8](=[CH:9][C:10]=3[O:28][CH2:27]2)[O:7][CH2:6][C:5]([C:4]2[CH:3]=[C:2]([OH:1])[CH:18]=[CH:17][CH:16]=2)=[CH:14]4)=[CH:21][CH:22]=1

Participants

5

Reactant 4

HCID 702EthanolHCID 712FormaldehydeHCID 7813p-ToluidineHCID 9813510HCID 9813510, compound

Product 1

HCID 25007594HCID 25007594, compoundYield 30%

Procedure

3′,7-Dihydroxyisoflav-3-ene (196 mg, 0.82 mmol) and p-toluidine (130 mg, 1.21 mmol) were dissolved in ethanol (1 ml). Formaldehyde solution (0.6 ml, 8.06 mmol, 37% wt.) was added and the reaction stirred at room temperature for 2 days. The resulting precipitate was collected to afford the title compound (99 mg, 30%).

Workup

  1. customThe resulting precipitate was collected

Sources & evidence

ORD record
ord-47521690866342b997494df5af411ad4
Source dataset
uspto-grants-2013_02
Patent number
US08367659B2

Reaction notes

Loading…