Ethanol → HCID 25007238, compound

HRID 383240Notes

Reaction equation

HRID 383240 reaction equation
[OH:1][C:2]1[CH:18]=[CH:17][C:5]([C:6]2[CH2:7][O:8][C:9]3[C:14]([CH:15]=2)=[CH:13][CH:12]=[C:11](O)[CH:10]=3)=[CH:4][CH:3]=1.[NH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH3:26])[CH:21]=1.[CH2:27]=[O:28].[CH2:29](O)C>>[C:22]1([CH3:26])[CH:23]=[CH:24][CH:25]=[C:20]([N:19]2[CH2:29][C:12]3[CH:13]=[C:14]4[C:9](=[CH:10][C:11]=3[O:28][CH2:27]2)[O:8][CH2:7][C:6]([C:5]2[CH:17]=[CH:18][C:2]([OH:1])=[CH:3][CH:4]=2)=[CH:15]4)[CH:21]=1

Participants

5

Reactant 4

HCID 702EthanolHCID 712FormaldehydeHCID 7934m-ToluidineHCID 219100Phenoxodiol

Product 1

HCID 25007238HCID 25007238, compoundYield 48%

Procedure

4′,7-Dihydroxyisoflav-3-ene (522 mg, 2.17 mmol) was dissolved in ethanol (8 ml). m-Toluidine (0.3 ml, 2.77 mmol) and formaldehyde solution (2 ml, 0.03 mol, 37% wt.) were added and the reaction stirred at room temperature for 3 days. The resulting precipitate was collected to afford the title compound (386 mg, 48%).

Workup

  1. customThe resulting precipitate was collected

Sources & evidence

ORD record
ord-cec70e4f00ad450e972f95aacc4aaabf
Source dataset
uspto-grants-2013_02
Patent number
US08367659B2

Reaction notes

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