3(2H)-Pyridazinone → 3-(6-Oxo-1,6-dihydropyridazin-3-yl)benzonitrile

HRID 383619Notes

Reaction equation

[C:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[C:7]#[N:8])(=O)[CH3:2].[N:12]1[NH:13][C:14](=[O:18])[CH:15]=CC=1>>[O:18]=[C:14]1[NH:13][N:12]=[C:1]([C:4]2[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=2)[C:7]#[N:8])[CH:2]=[CH:15]1

Participants

Reactant 2

HCID 681533(2H)-Pyridazinone

HCID 802223-Acetylbenzonitrile

Product 1

HCID 203265203-(6-Oxo-1,6-dihydropyridazin-3-yl)benzonitrile

Procedure

7.3 g of 3-acetylbenzonitrile are converted into the pyridazinone in accordance with GWP 1.

Sources & evidence

ORD record: ord-5e1d125202464801a3861883bd172eb3
Source dataset: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08367668B2

Reaction notes

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