m-Nitroacetophenone → 6-(3-nitrophenyl)pyridazin-3-ol

HRID 383622Notes

Reaction equation

[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-:12])=[O:11])[CH:5]=1)=O.[N:13]1[NH:14][C:15](=[O:19])[CH:16]=CC=1>>[O:19]=[C:15]1[NH:14][N:13]=[C:2]([C:4]2[CH:5]=[C:6]([N+:10]([O-:12])=[O:11])[CH:7]=[CH:8][CH:9]=2)[CH:1]=[CH:16]1

Participants

Reactant 2

HCID 8494m-Nitroacetophenone

HCID 681533(2H)-Pyridazinone

Product 1

HCID 121965616-(3-nitrophenyl)pyridazin-3-ol

Procedure

18 g of 3-nitroacetophenone are converted into the pyridazinone in accordance GWP 1.

Sources & evidence

ORD record: ord-e5ea391d0b01484db1c67b07a85b3e72
Source dataset: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08367668B2

Reaction notes

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