3(2H)-Pyridazinone → HCID 59406769, compound
Reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([CH2:10][C:11]([OH:13])=[O:12])[CH:7]=[CH:8][CH:9]=1)(=O)[CH3:2].[N:14]1[NH:15][C:16](=[O:20])[CH:17]=CC=1>>[O:20]=[C:16]1[NH:15][N:14]=[C:1]([C:4]2[CH:5]=[C:6]([CH2:10][C:11]([OH:13])=[O:12])[CH:7]=[CH:8][CH:9]=2)[CH:2]=[CH:17]1Participants
3
Procedure
5 g of 3-acetylphenylacetic acid (preparation described in Can. J. Chem.; 82; 12; 2004; 1760-1768) are converted into the pyridazinone in accordance with GWP 1.
Sources & evidence
- ORD record
- ord-d4405149de234c8a817c06cc2445b14c
- Source dataset
- uspto-grants-2013_02
- Patent number
- US08367668B2
Reaction notes
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