3(2H)-Pyridazinone → HCID 59406737, compound

HRID 383626Notes

Reaction equation

HRID 383626 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([OH:13])=[O:12])=[CH:6][CH:5]=1)(=O)[CH3:2].[N:14]1[NH:15][C:16](=[O:20])[CH:17]=CC=1>>[O:20]=[C:16]1[NH:15][N:14]=[C:1]([C:4]2[CH:9]=[CH:8][C:7]([CH2:10][C:11]([OH:13])=[O:12])=[CH:6][CH:5]=2)[CH:2]=[CH:17]1

Participants

3

Reactant 2

HCID 681533(2H)-PyridazinoneHCID 11469398(4-acetylphenyl)acetic acid

Product 1

HCID 59406737HCID 59406737, compound

Procedure

15 g of 4-acetylphenylacetic acid (preparation described in Can. J. Chem.; 82; 12; 2004; 1760-1768) are converted into the pyridazinone in accordance with GWP 1.

Sources & evidence

ORD record
ord-3acdeba441534446b9a7e73e8b2ac802
Source dataset
uspto-grants-2013_02
Patent number
US08367668B2

Reaction notes

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