Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3-(Morpholin-4-ylmethyl)aniline | HCID 1096406 | — |
| Reactant | 5-Chloropyrazolo(1,5-a)pyrimidine-3-carbaldehyde | HCID 58196401 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 58196499 | HCID 58196499 | — |
Reaction Steps
To 5-chloropyrazolo[1,5-a]pyrimidine-3-carbaldehyde (30 mg, 0.166 mmol) in DMF was added 3-(morpholinomethyl)aniline (233 mg, 1.213 mmol). The mixture was heated in microwave for 40 minutes at 140° C. Water was added and the solid formed was isolated by filtration to yield 5-(3-(morpholinomethyl)phenylamino)pyrazolo[1,5-a]pyrimidine-3-carbaldehyde. LCMS (M+1=338)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08367681B2 |
|---|
| Source dataset | uspto-grants-2013_02 |
|---|
| ORD ID | ord-3659a7c95bc4438eaaaf5ce99f1d1468 |
|---|
| Source note | uspto-grants-2013_02 |
|---|
