反应详情

Hydrazine monohydrate (1 mL, 20.58 mmol) was added to an ethanol (20 mL) solution of the compound (1.45 g, 4.21 mmol) synthesized in (1), and the mixture was stirred at room temperature for 24 hours. The reaction solution was filtered, and the filtrate was concentrated under reduced pressure. The residue was re-suspended in ethanol, and allowed to stand under ice-cooled conditions. After filtration, the filtrate was concentrated under reduced pressure to obtain the target (823 mg, 91%).

1. filtrationThe reaction solution was filtered
2. concentrationthe filtrate was concentrated under reduced pressure
3. temperaturecooled conditions
4. filtrationAfter filtration
5. concentrationthe filtrate was concentrated under reduced pressure
6. customto obtain the target (823 mg, 91%)