Hydrochloric Acid → HCID 59291346, compound

Participants

Reaction Steps

To a solution of methyl 2-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate in EtOH was added a 1 M aqueous NaOH solution, followed by heating under reflux for 5 hours. The reaction mixture was adjusted into pH=2 by addition of 1 M hydrochloric acid, and the solid precipitated was collected by filtration, and washed with water to obtain 2-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid as a white solid.

Provenance & Evidence