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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 384125Generated: October 31, 2026

HCID 86641944, compound → HCID 178515868, compound

https://huagongshe.com/reaction/384125

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86641944HCID 86641944—
SolventAcetic AcidHCID 176—
SolventHydrochloric AcidHCID 313—
ProductHCID 178515868HCID 178515868—

Reaction Steps

To a solution of N-hydroxy-3-oxo-4-(4-((2-phenoxybenzyl)oxy)phenyl)butanamide (17.2 mg) in acetic acid (0.2 ml), 0.05 ml of concentrated hydrochloric acid was added, and the reaction solution was stirred overnight at room temperature. The solvent was distilled off under reduced pressure, and the residue obtained was purified by preparative thin layer chromatography (Kieselgel™ 60 F254, Art5744, made by Merck & Co., hexane/ethyl acetate (1:1) to afford the title compound as a yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367708B2
Source datasetuspto-grants-2013_02
ORD IDord-8537372c91304d5881a9630d28a0b30f
Source noteuspto-grants-2013_02