HuagongsheHuagongshe Chemistry Print Report · For research reference only
Peracetic Acid → 2-(Methylsulfinyl)-4-(1-phenylcyclopropylamino)pyrimidine-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Peracetic Acid | HCID 6585 | — |
| Reactant | 2-(Methylthio)-4-(1-phenylcyclopropylamino)pyrimidine-5-carboxamide | HCID 58098664 | — |
| Solvent | 2-Oxopropiononitrile | HCID 69430 | — |
| Product | 2-(Methylsulfinyl)-4-(1-phenylcyclopropylamino)pyrimidine-5-carboxamide | HCID 58098785 | — |
Reaction Steps
To a suspension of 2-(methylthio)-4-(1-phenylcyclopropylamino)pyrimidine-5-carboxamide (636 mg) in AcCN (3 mL) was added AcOOH (39% in AcOH, 0.7 mL). The mixture was stirred at room temperature for 20 h, and the solids were collected by filtration and dried in vacuo to give 2-(methylsulfinyl)-4-(1-phenylcyclopropylamino) pyrimidine-5-carboxamide (530 mg). MS 317.2 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367689B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-749d854734f4479f932c45cf72b7d6c7 |
| Source note | uspto-grants-2013_02 |