反应详情

To a solution of (S)-1-methyl-N-(3-nitrophenyl)pyrrolidine-2-carboxamide (crude from step 1) in MeOH (5 ml) was added Pd/C (50 mg), charged with H2 (1 atm), after stirring for 3 h, Pd/C was filtered off and the filtrate was concentrated to give (S)-N-(3-aminophenyl)-1-methylpyrrolidine-2-carboxamide (350 mg).

1. additioncharged with H2 (1 atm)
2. filtrationPd/C was filtered off
3. concentrationthe filtrate was concentrated