HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-methyl-N-(3-nitrophenyl)pyrrolidine-2-carboxamide → HCID 58098798, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-methyl-N-(3-nitrophenyl)pyrrolidine-2-carboxamide | HCID 58098896 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 58098798 | HCID 58098798 | — |
Reaction Steps
To a solution of (S)-1-methyl-N-(3-nitrophenyl)pyrrolidine-2-carboxamide (crude from step 1) in MeOH (5 ml) was added Pd/C (50 mg), charged with H2 (1 atm), after stirring for 3 h, Pd/C was filtered off and the filtrate was concentrated to give (S)-N-(3-aminophenyl)-1-methylpyrrolidine-2-carboxamide (350 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367689B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-dc68127a023a4b5dbcbc69123128a21a |
| Source note | uspto-grants-2013_02 |