HCID 59526915, compound → HCID 19733794, compound

HRID 384446Notes

Reaction equation

HRID 384446 reaction equation
[CH3:1][C:2]([CH3:18])([CH3:17])[CH2:3][O:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9]CC1C=CC=CC=1>C(O)(=O)C.[Pd]>[CH3:1][C:2]([CH3:18])([CH3:17])[CH2:3][O:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9]

Participants

4

Reactant 1

HCID 59526915HCID 59526915, compound

Product 1

HCID 19733794HCID 19733794, compoundYield 27.8%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolvent

Procedure

To a solution of {[4-(2,2-dimethylpropoxy)butoxy]methyl}benzene (1.50 g) in acetic acid (30 mL) was added 10% palladium-activated carbon (500 mg), followed by stirring under hydrogen atmosphere for 3 hours. The catalyst was removed by filtration, and the solvent was evaporated under reduced pressure to obtain 4-(2,2-dimethylpropoxy)butan-1-ol (267 mg).

Workup

  1. customThe catalyst was removed by filtration
  2. customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-c7ea222b1c7a4e3cb94b862412a22ff3
Source dataset
uspto-grants-2013_02
Patent number
US08367702B2

Reaction notes

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