(3-Aminopropyl)triethoxysilane → HCID 123912826, compound

HRID 384598Notes

Reaction equation

HRID 384598 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][Si:5](OCC)(OCC)OCC.[CH3:15][O:16][C:17]1[CH:33]=[CH:32][C:20]([C:21]([C:23]23[O:30][C:29](=[O:31])[CH:28]2[CH2:27][CH2:26][CH2:25][CH2:24]3)=[O:22])=[CH:19][CH:18]=1>C(Cl)Cl>[SiH3:5][CH2:4][CH2:3][CH2:2][NH:1][C:29]([CH:28]1[CH2:27][CH2:26][CH2:25][CH2:24][C:23]1([OH:30])[C:21](=[O:22])[C:20]1[CH:19]=[CH:18][C:17]([O:16][CH3:15])=[CH:33][CH:32]=1)=[O:31]

Participants

4

Reactant 2

HCID 13521(3-Aminopropyl)triethoxysilaneHCID 86629708HCID 86629708, compound

Product 1

HCID 123912826HCID 123912826, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

3-Aminopropyltriethoxysilane (22.14 g, 0.100 mol) is added to a solution of 26.03 g (0.100 mol) of 6-(4-methoxy-benzoyl)-7-oxa-bicyclo[4.2.0]octan-8-one in methylene chloride. The reaction mixture is heated at reflux for several hours and monitored by thin layer chromatography. Upon completion of the reaction, solvent is evaporated to obtain the title compound.

Workup

  1. temperatureThe reaction mixture is heated
  2. temperatureat reflux for several hours
  3. customUpon completion of the reaction, solvent
  4. customis evaporated

Sources & evidence

ORD record
ord-e2c8c5c7d85d49189264da01c1161d4b
Source dataset
uspto-grants-2013_02
Patent number
US08367743B2

Reaction notes

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