Tetrahydro-4H-pyran-4-ol → 5-Bromo-3-methyl-2-(oxan-4-yloxy)pyridine

HRID 384884Notes

Reaction equation

HRID 384884 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH3:9])[C:5]([OH:8])=[N:6][CH:7]=1.[O:10]1[CH2:15][CH2:14][CH:13](O)[CH2:12][CH2:11]1>>[Br:1][C:2]1[CH:3]=[C:4]([CH3:9])[C:5]([O:8][CH:13]2[CH2:14][CH2:15][O:10][CH2:11][CH2:12]2)=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 74956Tetrahydro-4H-pyran-4-olHCID 178422464HCID 178422464, compound

Product 1

HCID 684106265-Bromo-3-methyl-2-(oxan-4-yloxy)pyridine

Procedure

The title compound was prepared from 5-bromo-2-hydroxy-3-methylpyridine and tetrahydro-4H-pyran-4-ol in analogy to Example 9c): colorless solid.

Sources & evidence

ORD record
ord-34ee81c0bb5a4a16b1732c3a1253f1be
Source dataset
uspto-grants-2013_02
Patent number
US08367838B2

Reaction notes

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