HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Dimethylamino)benzeneboronic acid → Rac-[1-(3,4-dichloro-phenyl)-2-(3'-dimethylamino-biphenyl-4-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Dimethylamino)benzeneboronic acid | HCID 2762527 | — |
| Reactant | Rac-[1-(3,4-dichloro-phenyl)-2-(4-iodo-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester | HCID 68409915 | — |
| Product | Rac-[1-(3,4-dichloro-phenyl)-2-(3'-dimethylamino-biphenyl-4-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester | HCID 68408636 | — |
Reaction Steps
The title compound was prepared from rac-[1-(3,4-dichloro-phenyl)-2-(4-iodo-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester and 3-(dimethylamino)phenylboronic acid in analogy to Example 1b): MS (ISP): 499.1 and 501.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367838B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-179356e6764b422bb6977b69a01589b5 |
| Source note | uspto-grants-2013_02 |