Hydrogen Peroxide → HCID 178418510, compound

HRID 3850Notes

Reaction equation

HRID 3850 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([S:9]([CH3:11])=[O:10])[CH:6]=[CH:5][C:4]=1[C:12]1[N:13]=[C:14]2[C:19](=[O:20])[NH:18][NH:17][CH:16]=[C:15]2[N:21]=1.[OH:22]O>C(O)(=O)C>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([S:9]([CH3:11])(=[O:22])=[O:10])[CH:6]=[CH:5][C:4]=1[C:12]1[N:13]=[C:14]2[C:19](=[O:20])[NH:18][NH:17][CH:16]=[C:15]2[N:21]=1

Participants

4

Reactant 2

HCID 784Hydrogen Peroxide2×HCID 178418521HCID 178418521, compound

Product 1

HCID 178418510HCID 178418510, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A quantity of 0.07 gm of 2-(2-methoxy-4-methylsulfinyl-phenyl)-5H-imidazo[4,5-d]pyridazin-4-one is dissolved in 5 ml of glacial acetic acid, mixed with 0.05 ml of 30% hydrogen peroxide, and stirred first for 55 minutes at ambient temperature then for two hours at 40°-50° C., Then, a further 0.05 ml of hydrogen peroxide are added, and the mixture is heated for another hour. The product precipitated is subjected to suction filtration and washed with ether.

Workup

  1. waitfor two hours at 40°-50° C.
  2. temperaturethe mixture is heated for another hour
  3. customThe product precipitated
  4. filtrationis subjected to suction filtration
  5. washwashed with ether

Sources & evidence

ORD record
ord-033061a22a0d4381887b3730bf5da3c7
Source dataset
uspto-grants-1988_02
Patent number
US04722929

Reaction notes

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