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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385121Generated: October 28, 2026

Oxalyl chloride → HCID 86668177, compound

https://huagongshe.com/reaction/385121

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxalyl chlorideHCID 65578—
ReactantHCID 68108612HCID 68108612—
SolventTolueneHCID 1140—
ProductHCID 86668177HCID 86668177—

Reaction Steps

To 4-methoxy-3-(pyrrolidine-1-carbonyl)-5-trifluoromethylbenzoic acid (785 mg), toluene (8 mL) and oxalyl chloride (0.64 mL) were added, and then the mixture was stirred at room temperature for 22 hours. The solvent was distilled off under reduced pressure and the obtained product was used for the synthesis of (d).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367843B2
Source datasetuspto-grants-2013_02
ORD IDord-348a273fc74649e3a137eb1da298f248
Source noteuspto-grants-2013_02