Water → HCID 68107964, compound

Participants

Reaction Steps

Methyl 4-methoxymethoxy-3-trifluoromethoxybenzoate (590 mg) was dissolved in chloroform (10 mL), and trifluoroacetic acid (5 mL) was added to the solution, and then the mixture was stirred at room temperature for 1 hour. Water was added to the solution, and then the mixture was extracted with chloroform. The organic layer was washed with saturated brine, and then dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure and the obtained residue was washed with n-hexane to obtain the title compound (346 mg) as a colorless crystal.

Provenance & Evidence