反应详情

A solution of the compound from Example 60A (6.73 g, 26.5 mmol) in ethanol (70 mL) was stirred with platinum dioxide (200 mg) under a hydrogen atmosphere at normal pressure for 3 h. The catalyst was removed by suction filtration, and the solvent was removed in vacuo. The residue was triturated with tert-butyl methyl ether, and the product was collected by suction filtration to yield 5.1 g (86%) as white crystals.

1. customThe catalyst was removed by suction filtration
2. customthe solvent was removed in vacuo
3. customThe residue was triturated with tert-butyl methyl ether
4. filtrationthe product was collected by suction filtration
5. customto yield 5.1 g (86%) as white crystals