HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-phenylthiophene-3-carboxamide → 2-{[5-(1-Hydroxy-1-methylethyl)pyridin-2-yl]amino}-5-phenylthiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-phenylthiophene-3-carboxamide | HCID 703965 | — |
| Reactant | 2-(6-Bromo-3-pyridyl)-2-propanol | HCID 22391973 | — |
| Product | 2-{[5-(1-Hydroxy-1-methylethyl)pyridin-2-yl]amino}-5-phenylthiophene-3-carboxamide | HCID 59526154 | — |
Reaction Steps
2-{[5-(1-Hydroxy-1-methylethyl)pyridin-2-yl]amino}-5-phenylthiophene-3-carboxamide was prepared using 2-(6-bromopyridin-3-yl)propan-2-ol (79.3 mg, 0.367 mmol) (for preparation, see WO 2004/050024 A2 Example 120 Step A) and 2-amino-5-phenylthiophene-3-carboxamide (80 mg, 0.367 mmol) as the starting materials according the general procedure in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367706B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-26b07a4a7cbe4fcea01ac56825099e70 |
| Source note | uspto-grants-2013_02 |