Methylamine → 1-(6-Bromopyridin-2-yl)-N-methylmethanamine
Reaction equation
[Br:1][C:2]1[N:7]=[C:6]([CH:8]=O)[CH:5]=[CH:4][CH:3]=1.[CH3:10][NH2:11]>>[Br:1][C:2]1[N:7]=[C:6]([CH2:8][NH:11][CH3:10])[CH:5]=[CH:4][CH:3]=1Participants
3
Procedure
The title compound was prepared according to the procedure in Example 45 Step 1 using 6-bromopyridine-2-carbaldehyde (0.50 g, 2.69 mmol) and methylamine (0.253 mg, 2.69 mmol) as the starting materials
Sources & evidence
- ORD record
- ord-3d4e40b1fd7c4ba1889a0cd63910469b
- Source dataset
- uspto-grants-2013_02
- Patent number
- US08367706B2
Reaction notes
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