HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-(4-fluorophenyl)thiophene-3-carboxamide → 2-{[6-(1-Azetidin-1-ylethyl)pyridin-2-yl]amino}-5-(4-fluorophenyl)thiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-(4-fluorophenyl)thiophene-3-carboxamide | HCID 9942771 | — |
| Reactant | 2-(1-Azetidin-1-ylethyl)-6-bromopyridine | HCID 59525565 | — |
| Product | 2-{[6-(1-Azetidin-1-ylethyl)pyridin-2-yl]amino}-5-(4-fluorophenyl)thiophene-3-carboxamide | HCID 59525668 | — |
Reaction Steps
The title compound was prepared according to the general procedure in Example 1 using 2-(1-azetidin-1-ylethyl)-6-bromopyridine (200 mg, 0.83 mmol) and 2-amino-5-(4-fluorophenyl)thiophene-3-carboxamide (216 mg, 0.91 mmol) as the starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367706B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-9c6f717968d1463fa8b33ad994daa41b |
| Source note | uspto-grants-2013_02 |