2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({6-[2-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-2-hydroxyethyl]pyridin-2-yl}amino)thiophene-3-carboxamide

関与物質

反応手順

The title compound was prepared according to the general procedure in Example 1 using 2-(6-bromopyridin-2-yl)-1-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)ethanol (0.11 g, 0.32 mmol) and 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (0.10 g, 0.32 mmol) as the starting materials.

情報源と証拠