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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385817Generated: October 31, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59525963, compound

https://huagongshe.com/reaction/385817

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ReactantHCID 59526108HCID 59526108—
ProductHCID 59525963HCID 59525963—

Reaction Steps

The title compound was prepared using the procedure listed in Example 1 with 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (0.11 g, 0.34 mmol) and benzyl (3S,4S)-4-(6-bromopyridin-2-yl)-3,4-dihydroxypiperidine-1-carboxylate (0.13 g, 0.33 mmol) as the starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-3daf0d118bcd48898a42db1ec321c4c2
Source noteuspto-grants-2013_02