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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385826Generated: October 31, 2026

2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59525705, compound

https://huagongshe.com/reaction/385826

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 58216638—
ReactantHCID 59526349HCID 59526349—
ProductHCID 59525705HCID 59525705—

Reaction Steps

The title compound was prepared as described in Example 1 using 2-amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (50 mg, 0.17 mmol) and benzyl[(6-bromopyridin-2-yl)methyl]{2-[(2-hydroxyethyl)amino]-2-oxoethyl}carbamate (110 mg, 0.26 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-6073b4f39cab414e961f93009a7e6c5f
Source noteuspto-grants-2013_02