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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385827Generated: October 31, 2026

2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59526203, compound

https://huagongshe.com/reaction/385827

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 58216638—
ReactantHCID 59526017HCID 59526017—
ProductHCID 59526203HCID 59526203—

Reaction Steps

The title compound was prepared as described in Example 1 with 2-amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (500 mg, 1.70 mmol) and N-[(benzyloxy)carbonyl]-N-[(6-bromopyridin-2-yl)methyl]glycine (Example 179, Step 3) (644 mg, 1.70 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-14c3854b3a3b407cba3a89b7f9d6d227
Source noteuspto-grants-2013_02