(2E)-4-(Dimethylamino)-2-butenoic acid hydrochloride → HCID 58116830, compound

Participants

Reaction Steps

In analogy to Example 89, the title compound was prepared from N-[1-(3-fluorobenzyl)-1H-indazol-5-yl]-6,7-dihydro-5H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidin-4-amine from Example 33A (51 mg, 0.12 mmol) and (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride from Example 1A (29 mg, 0.17 mmol) to yield 30 mg (44%).

Provenance & Evidence