HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromopyridine-2-carboxylic acid → (2R)-4-[(6-Bromopyridin-2-yl)carbonyl]-2-methylmorpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromopyridine-2-carboxylic acid | HCID 593919 | — |
| Reactant | (2R)-2-Methylmorpholine hydrochloride | HCID 42609645 | — |
| Product | (2R)-4-[(6-Bromopyridin-2-yl)carbonyl]-2-methylmorpholine | HCID 59526327 | — |
Reaction Steps
The title compound was prepared as described in Example 283, Step 1 using (2R)-2-methylmorpholine hydrochloride (124 mg, 0.90 mmol) and 6-bromopyridine-2-carboxylic acid (150 mg, 0.74 mmol) as starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367706B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-d9f06d4a3c6348fc943ded61811e9145 |
| Source note | uspto-grants-2013_02 |