反应详情

To excess thionyl chloride (250 mL) at 0° C. was added 2-(1-methyl-1H-pyrazol-4-yl)ethanol (82 g, 0.651 mol). The reaction mixture was heated to reflux for 15 minutes. The excess thionyl chloride was removed in vacuo and the crude product was purified by recrystallization from EtOH to afford the title compound.

1. temperatureThe reaction mixture was heated
2. temperatureto reflux for 15 minutes
3. customThe excess thionyl chloride was removed in vacuo
4. customthe crude product was purified by recrystallization from EtOH