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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 385893Generated: October 31, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59525816, compound

https://huagongshe.com/reaction/385893

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ReactantN-[(6-bromopyridin-2-yl)methyl]-2-cyanoacetamideHCID 59526353—
ProductHCID 59525816HCID 59525816—

Reaction Steps

The title compound was prepared using the procedure described in Example 1 with 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (0.12 g, 0.38 mmol) and N-[(6-bromopyridin-2-yl)methyl]-2-cyanoacetamide (0.96 g, 0.38 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-9ccb331fefdd4903b9d77dda4efbde3f
Source noteuspto-grants-2013_02