HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine → 5-[2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[5-(5-methyl-1,3,4-oxadiazol-2-yl)pyridin-2-yl]amino}thiophene-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine | HCID 12637511 | — |
| Reactant | 2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide | HCID 58216638 | — |
| Product | 5-[2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[5-(5-methyl-1,3,4-oxadiazol-2-yl)pyridin-2-yl]amino}thiophene-3-carboxamide | HCID 59525819 | — |
Reaction Steps
The title compound was prepared as described in Example 1 using 2-amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (90 mg, 0.31 mmol) and 2-chloro-5-(5-methyl-1,3,4-oxadiazol-2-yl)pyridine (60 mg, 0.31 mmol) as starting materials.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367706B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-38596cfabfbd4a3a945df0643194abac |
| Source note | uspto-grants-2013_02 |