Acetic acid, azido-, ethyl ester → Ethyl[4-(6-chloro-2-methylpyridin-3-yl)-1h-1,2,3-triazol-1-yl]acetate

HRID 385969Notes

Reaction equation

HRID 385969 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([CH3:8])[C:5]([C:9]#[CH:10])=[CH:4][CH:3]=1.[CH2:11]([O:13][C:14](=[O:19])[CH2:15][N:16]=[N+:17]=[N-:18])[CH3:12]>>[CH2:11]([O:13][C:14](=[O:19])[CH2:15][N:16]1[CH:10]=[C:9]([C:5]2[C:6]([CH3:8])=[N:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[N:18]=[N:17]1)[CH3:12]

Participants

3

Reactant 2

HCID 69480Acetic acid, azido-, ethyl esterHCID 127097396-Chloro-3-ethynyl-2-methylpyridine

Product 1

HCID 59525782Ethyl[4-(6-chloro-2-methylpyridin-3-yl)-1h-1,2,3-triazol-1-yl]acetate

Procedure

The title compound was prepared as described in Example 413, Step 2 using 6-chloro-3-ethynyl-2-methylpyridine (250 mg, 1.65 mmol) and ethylazidoacetate (0.93 ml, 1.65 mmol) as starting materials

Sources & evidence

ORD record
ord-0c31978d95e04f518bcadce7d4da3ce4
Source dataset
uspto-grants-2013_02
Patent number
US08367706B2

Reaction notes

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