HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Morpholine-3-carboxylic acid amide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | tert-Butyl 3-carbamoylmorpholine-4-carboxylate | HCID 21098189 | — |
| Product | Morpholine-3-carboxylic acid amide hydrochloride | HCID 67166308 | — |
Reaction Steps
1,1-Dimethylethyl 3-(aminocarbonyl)morpholine-4-carboxylate (0.48 g, 2.085 mmol) was taken up in 4 M HCl in dioxane (5 mL, 10.00 mmol) and maintained at room temperature overnight. The solvent was removed in vacuo to afford the title compound as a pale yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367706B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-11ae47b014e3454b84fe5e46e12c8be8 |
| Source note | uspto-grants-2013_02 |