2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(2-fluoro-1-morpholin-4-ylethyl)pyridin-2-yl]amino}thiophene-3-carboxamide

Participants

Reaction Steps

The title compound was prepared according to the general procedure in Example 1 using 4-[1-(6-bromopyridin-2-yl)-2-fluoroethyl]morpholine (36.3 mg, 0.13 mmol) and 2-amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (37 mg, 0.13 mmol) as the starting materials.

Provenance & Evidence