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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 386019Generated: October 29, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59525826, compound

https://huagongshe.com/reaction/386019

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ReactantHCID 59526378HCID 59526378—
ProductHCID 59525826HCID 59525826—

Reaction Steps

The title compound was synthesized from methyl[(6-chloro-2-methylpyridin-3-yl)methyl]carbamate (85 mg, 0.40 mmol) and 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (130 mg, 0.42 mmol) according to the general procedure in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-285553175e2b4d338783174bd20f0169
Source noteuspto-grants-2013_02