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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 386094Generated: November 1, 2026

HCID 59525582, compound → HCID 59526102, compound

https://huagongshe.com/reaction/386094

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59525582HCID 59525582—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Reactant3-[(4-Bromopyrimidin-2-yl)methyl]-1,3-oxazolidin-2-oneHCID 59525922—
ProductHCID 59526102HCID 59526102—

Reaction Steps

The title compound was prepared according to Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (85 mg, 0.27 mmol) and the mixture of 3-[(4-chloropyrimidin-2-yl)methyl]-1,3-oxazolidin-2-one (21.5 mg, 0.10 mmol) and 3-[(4-bromopyrimidin-2-yl)methyl]-1,3-oxazolidin-2-one (44.2 mg, 0.17 mmol) as the starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-be5e9d0b1dcb476a921b148e72c5862d
Source noteuspto-grants-2013_02