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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 386103Generated: October 30, 2026

HCID 59525612, compound → HCID 59525935, compound

https://huagongshe.com/reaction/386103

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59525612HCID 59525612—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ReactantHCID 59526317HCID 59526317—
ProductHCID 59525935HCID 59525935—

Reaction Steps

The title compound was prepared by the procedure in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (62.3 mg, 0.200 mmol) and a mixture of 4-bromo-2-{[4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl]methyl}pyrimidine (38 mg, 0.122 mmol) and 4-chloro-2-{[4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl]methyl}pyrimidine (21 mg, 0.078 mmol) as the starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-381f611e1d274caa9e373714d36a78fa
Source noteuspto-grants-2013_02