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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 386105Generated: October 31, 2026

4-Chloropyrimidine-2-carbonitrile → HCID 59525709, compound

https://huagongshe.com/reaction/386105

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloropyrimidine-2-carbonitrileHCID 45787493—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ProductHCID 59525709HCID 59525709—

Reaction Steps

The title compound was prepared as described in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (113 mg, 0.36 mmol) and 4-chloropyrimidine-2-carbonitrile (51 mg, 0.36 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-2d1c2620bf9243959beec320af523f85
Source noteuspto-grants-2013_02