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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 386107Generated: October 29, 2026

2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → HCID 59525981, compound

https://huagongshe.com/reaction/386107

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 58216638—
ReactantHCID 59526148HCID 59526148—
ProductHCID 59525981HCID 59525981—

Reaction Steps

The title compound was prepared as described in Example 1 using 2-amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (68 mg, 0.23 mmol) and 1-(4-chloropyrimidin-2-yl)-2,2,2-trifluoroethanol (49 mg, 0.23 mmol) as starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367706B2
Source datasetuspto-grants-2013_02
ORD IDord-004b1154fed4407ebd5f5370174c102c
Source noteuspto-grants-2013_02