Trifluoroacetic acid → HCID 59526009, compound

Participants

Reaction Steps

5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({6-[2-(trimethylsilyl)ethoxy]pyridazin-3-yl}amino)thiophene-3-carboxamide (0.61 g, 1.20 mmol) was taken up in DCM (12 mL) and TFA (0.4 mL) was added. After 30 minutes at room temperature, saturated NaHCO3 was added. The resulting precipitate was collected by filtration and triturated in DCM to give the title compound as a yellow solid.

Provenance & Evidence