HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59289076, compound → HCID 59289027, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59289076 | HCID 59289076 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 59289027 | HCID 59289027 | — |
Reaction Steps
A solution of 3-[4′-(5,5-Dimethyl-[1,3]dioxan-2-yl)-bicyclohexyl-4-yl]-propionic acid ethyl ester (17 g, 45 mmol) in toluene (200 ml) and formic acid (70 ml) is stirred overnight at 80° C. The solution is washed with water, dried (Na2SO4), concentrated and recrystallised to give 3-(4′-formyl-bicyclohexyl-4-yl)-propionic acid ethyl ester as colourless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08372307B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-7ba0a33256204dcfa02a1731b548c37d |
| Source note | uspto-grants-2013_02 |