Triethylamine → HCID 59289086, compound

Participants

Reaction Steps

2-(4-propyl-cyclohexylmethyl)-butan-1-ol (13 g, 61.2 mmol) is dissolved in dichloromethane (50 ml) and triethylamine (3.5 ml) and a solution of methacryloyl chloride (2.2 ml, 21.8 mmol) in dichloromethane (30 ml) is added dropwise at 0° C. The reaction is stirred overnight, evaporated, filtered through silica with heptane/ethyl acetate (19:1) and the crude product is crystallised from ethanol to give acrylic acid 2-(4-propyl-cyclohexylmethyl)-butyl ester as a colourless oil.

Provenance & Evidence