HCID 56646750, compound → 2-(3-([Bis-[(benzyl)oxy]]phosphoryl)oxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one

HRID 38661Notes

Reaction equation

P([O:19][C:20]1[C:29]2[C:24](=[CH:25][C:26]3[O:32][CH2:31][O:30][C:27]=3[CH:28]=2)[N:23]=[C:22]([C:33]2[CH:38]=[C:37]([O:39][CH3:40])[CH:36]=[C:35]([O:41][P:42]([O:52][CH2:53][C:54]3[CH:59]=[CH:58][CH:57]=[CH:56][CH:55]=3)([O:44][CH2:45][C:46]3[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=3)=[O:43])[CH:34]=2)[CH:21]=1)(OCC1C=CC=CC=1)(OCC1C=CC=CC=1)=O>CO>[CH2:53]([O:52][P:42]([O:41][C:35]1[CH:34]=[C:33]([C:22]2[CH2:21][C:20](=[O:19])[C:29]3[C:24](=[CH:25][C:26]4[O:32][CH2:31][O:30][C:27]=4[CH:28]=3)[N:23]=2)[CH:38]=[C:37]([O:39][CH3:40])[CH:36]=1)([O:44][CH2:45][C:46]1[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=1)=[O:43])[C:54]1[CH:55]=[CH:56][CH:57]=[CH:58][CH:59]=1

Participants

Conditions

Temperature: 25 °C

Procedure

A suspension of 0.92 g (1.11 mmol) of 167 in 100 mL of methanol was stirred at 25° C. for 48 h. The precipitates were collected and purified by column chromatography (SiO2, EtOAc) to give 168.

Workup

customThe precipitates were collected
custompurified by column chromatography (SiO2, EtOAc)

Sources & evidence

ORD record: ord-6ff94a40cbe94c12bb7d85c1cae3b3fd
Source dataset: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08524740B2

Reaction notes

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